Author: rachelcbm

“Proteins that are engineered in the laboratory for pharmaceutical use are referred to as therapeutic proteins”. Protein-based therapeutics are highly successful in clinic and currently enjoy unprecedented recognition of their potential. Recently approved recombinant protein therapeutics have been developed to treat a wide variety of clinical indications, including cancers, autoimmunity/inflammation, exposure to infectious agents, and…

Defects in the Tpo‑Tpo R signaling pathway are associated with a variety of platelet disorders. The 353 amino acid (aa) human Tpo precursor is cleaved to yield the 332 aa mature protein. Mature human Tpo shares approximately 70% aa sequence homology with mouse and rat Tpo. It is an 80‑85 kDa protein that consists of…

“Proteins that are engineered in the laboratory for pharmaceutical use are referred to as therapeutic proteins”. Protein-based therapeutics are highly successful in clinic and currently enjoy unprecedented recognition of their potential. Recently approved recombinant protein therapeutics have been developed to treat a wide variety of clinical indications, including cancers, autoimmunity/inflammation, exposure to infectious agents, and…